Job Description The Wagle laboratory based at Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT focuses on translational cancer genomics and precision cancer medicine.The major goals of the laboratory are to use systematic genomic and molecular characterization of tumor samples from patients with cancer to better understand the molecular determinants of tumorigenesis characterize mechanisms of therapeutic response and resistance and identify novel characteristics of tumors that might aid in clinical decision-making.

Job Description Overview: The Karczewski Laboratory at the Broad Institute is seeking highly qualified postdoctoral candidates to perform genomics data science research across a spectrum of population genetics and disease association studies within the Stanley Center for Psychiatric Research and the Program in Medical and Population Genetics.Successful candidates are expected to excel at critical thinking be quick learners for new analytical approaches and capable of applying or developing novel computational methods for solving complex problems.

Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng Co-Director of the Stanley Center for Psychiatric Research The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses through groundbreaking basic and translational research.Based on unprecedented insights into the genetic basis of psychiatric diseases the Stanley Center aims to uncover key disease mechanisms and discover novel therapeutics.

Job Description Postdoctoral Associate Fungal Genomics The Broad Institute of MIT and Harvard is seeking to hire a Postdoctoral Associate to join the Infectious Disease and Microbiome Program and work on genomic analysis of fungal pathogens affecting human health.The successful applicant would join an interdisciplinary team studying the genomic basis of pathogen evolution and host-pathogen interactions in the Broad Institute Genomic Center for Infectious Disease.

Job Description OVERVIEW/ OVERALL RESPONSIBILITY : The Khera Laboratory based within the Cardiovascular Disease Initiative at the Broad Institute of MIT and Harvard and the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking exceptional computational scientists in computational biology to join our community.Prior work in the group has pioneered the use of polygenic scores to quantify inherited susceptibility to disease studied the interaction of genetic factors with lifestyle and environmental exposures in determining health outcomes and identified new genetic drivers of cardiometabolic conditions.

Job Description The Proteomics Platform at the Broad Institute (Steve Carr PI) is looking for a motivated post-doctoral associate in computational proteomics who will focus on developing and applying innovative computational approaches to analyzing proteogenomics data spanning genomics transcriptomics proteomics phosphoproteomics and other posttranslational modifications from cancer cardiovascular and other diseases being actively studied at Broad.The work will involve analysis of large-scale multi-omics data via pathway and network analysis integrated with statistical and machine learning approaches to derive biological insights and identify therapeutic opportunities.

Job Description Computational Biologist I/II: Spatial transcriptomics and proteomics The Broad Institute of MIT & Harvard is looking for two Computational Biologists to join the Optical Profiling Platform (OPP) directed by Dr. Sami Farhi to advance large-scale analysis efforts in the Human Tumor Atlas and Brain Initiative Cell Census Network.OPP seeks to translate advances in optics and imaging to the broader biological community to impact pressing problems in biology and human health.

Job Description JOB DESCRIPTION We are seeking an exceptional highly motivated computational postdoctoral fellow to join a new team at the Broad Institute to build a Human Gene Regulation Map and link this Map to Cellular Programs.This position will be embedded in the Claussnitzer lab in close collaboration with the Lander and Engreitz labs and will seek to understand the fundamental wiring of the genome in mesenchymal stem cell lineages and build a reference atlas for discovering molecular and cellular programs underlying common genetic diseases to launch new therapeutic drug discovery programs based on these human genetic insights.

Job Description The Broad Institute has a long history of generating massive genomic datasets from the Human Genome Project to The Cancer Genome Atlas and developing cutting edge analytical tools for large-scale genomic analyses.The Broad Genomics Platform is the largest generator of human sequencing data to support impactful science for both research and clinical communities.

Job Description The Lage Lab at theNovo Nordisk Foundation Center for Genomic Mechanisms of DiseaseandStanley Centeris seeking a self-motivated skilled postdoctoral associate with a Ph.D. in the fields of bioinformatics statistical genetics computational biology or complex trait genetics to study the genetic mechanisms of complex diseases at an unprecedented scale and resolution.We develop and apply computational technologies to functionally interpret largegenomic datasets and to understand how genetic variation results in common genetic diseases.

Job Description Apply your computational and statistical skills to analyzing exciting datasets and designing algorithms.This is a rare opportunity to be part of an exciting collaborative team of clinicians biochemists cell and computational biologists that work together in Vamsi Moothas laboratory to study mitochondria and their role in human disease.

Job Description OVERALL RESPONSIBILITY We are seeking a motivated Computational Scientist to join Sheng Lab the at the Broad Institute of MIT and Harvard.Aligned with the mission of Stanley Center we are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders anticipating that our research would be potentially useful for identifying more effective biomarkers and treatments.

Job Description The Broad Institute is an amazing place - we exist to apply our deep knowledge of human genetics to empower a revolution in biomedicine and accelerate the pace at which the world conquers disease.The Broad Institutes Center for the Development of Therapeutics (CDoT) and its team of professional drug hunters partner with faculty at MIT Harvard and the Harvard teaching hospitals to translate emerging biological insights into novel therapeutic strategies.

Job Description The research groups of Ramnik Xavier and Caroline Uhler are seeking highly motivated postdoctoral researchers in the field of computational biology.This role involves the development and application of machine learning methods towards systems immunology studies.

Job Description OVERALL RESPONSIBILITY We are seeking a motivated Associate Computational Scientist (ACB) to join the Sheng Lab at the Broad Institute of MIT and Harvard .We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders.

Job Description Associate Computational Biologist - GTEx/GRO The Broad Institute is launching a new effort the Gene Regulation Observatory (GRO).The mission of the GRO is to deeply understand fundamental processes of genome regulation in single cells and spans interests from many of the Broads programs and communities including the Epigenomics & Cell Circuits MPG and Stanley center programs and communities.

Job Description Overview : The Getz lab is looking for a highly motivated and talented individual with computational background to join the CGA Cancer Resistance team.The lab has undertaken an ambitious 5-year project aimed at discovering the basis of drug resistance in cancer.

Job Description The Macosko Lab part of the Stanley Center for Psychiatric Research at the Broad Institute is seeking self-motivated creative computational postdoctoral candidates to work at the exciting intersection of new genomics technology and disease.Using cutting edge single cell and spatial genomics technologies we are working to clarify mechanisms of neuropsychiatric disease and proffer new therapeutic targets.A strong background in computational biology is required; and specifically experience with analyzing high-dimensional genomics datasets is preferred.Some fluency with biology and/or neuroscience is ideal as is the ability to adapt quickly and be part of a cross-functional team in a rapidly changing environment.

Job Description We are seeking a highly motivated associate computational biologist to join a new team at the Broad Institute to build a Human Gene Regulation Map.This effort will seek to understand the fundamental wiring of the noncoding genome and build a reference map for uncovering biological mechanisms on common genetic diseases.

Job Description The Getz Lab is looking for exceptional candidates to join the Cancer Genome Analysis group.The successful candidates will join an interdisciplinary team of bioinformatics analysts software engineers genome biologists and clinicians who are working together to identify mutations that lead to cancer and to discover new cancer therapeutics.