The Knowledge Systems Group (KSG) at Dana-Farber Cancer Institute is seeking an experienced Bioinformatics Data Manager to spearhead multiple bioinformatics big data projects. The role is primarily focused on making standardized genomic and clinical data sets available to the scientific community via open-access open-source platforms. The Knowledge Systems Group (KSG) is an applied bioinformatics group focused on developing open-source platforms for cancer genomics research and precision cancer medicine. We are computational biologists software engineers and project managers all united in using our skills to make a difference in cancer patients' lives. We support several projects including the NCI Human Tumor Atlas Network (HTAN) the Cancer Immunologic Data Commons (CIDC) and the cBioPortal for Cancer Genomics. We also support DFCIs institutional clinical sequencing and precision cancer medicine initiatives.

Located in Boston and the surrounding communities Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer HIV/AIDS and related diseases. We strive to create an inclusive diverse and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment we educate tomorrow's physician/researchers and we work with amazing partners including other Harvard Medical School-affiliated hospitals.

As the Bioinformatics Data Manager you will be responsible for:

• Consulting with external stakeholders to understand and define consortium requirements regarding data access data analysis and data sharing.
• Understanding new genomic assays and defining new data standards.
• Understanding and defining clinical data standards and creating clinical data mappings for harmonized clinical data sets.
• Translating consortium requirements into well-defined project specifications for handoff to software engineering team.
• Integrating and harmonizing data sets in preparation for cross-trial and cross-cancer analysis.
• Working with data producers and ensuring the transfer of new standardized data sets into cloud-based data sharing platforms.

• Strong background and interest in cancer genomics.
• Strong background and interest in open access science.
• MS or PhD in bioinformatics or computational biology.
• Experience developing genomic and clinical data standards and ontologies.
• Experience managing genomic assay data including single cell RNASeq and multiplex imaging.
• Experience managing complex bioinformatics projects including stakeholder management and ability to multitask multiple project deadlines.
• Working experience with data sharing platforms including dbGAP or NCI Cloud Resources.

Due to COVID-19 KSG is currently in hybrid mode with most members working remotely but some members working on site 2-3 days / week. For this position we are open to remote/hybrid workers in Massachusetts New Hampshire or Rhode Island.

At Dana-Farber Cancer Institute we work every day to create an innovative caring and inclusive environment where every patient family and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals neither do we. If working in this kind of organization inspires you we encourage you to apply.