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Postdoctoral Associate - Xavier Lab

Organisation Name: Broad Institute
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Job Description

Job Description

The Xavier lab is seeking highly motivated postdoctoral researchers with PhD degrees in molecular biology biochemistry immunology or computational biology.

Recent publications from the lab include:

  • Development and application of the PhaseFinder algorithm to examine the diversity of phase variation uncovering enrichment of invertons in host-associated bacterial species and inverton mediated antibiotic resistance and interhost adaptation. [Jiang et al Science 2019 Jan;363(6423):181-187 PMID:30630933]

  • Single-cell resolution mapping of the enteric nervous system (ENS) reveals extensive diversity of neuron subsets with conserved transcriptional programs providing a roadmap for dissecting the role of the ENS in health and disease. [Drokhlyansky et al Cell 2020 Sep 17;182(6):1606-1622 PMID:32888429]

  • Cellular adaptation to ER stress is mediated by the transcriptional regulator QRICH1 which determines cell fate through control of protein translation and secretory networks that are upregulated in inflammatory pathologies. [You et al. Science 2021 Jan 1;371(6524):696-708 PMID:33384352]

  • Multi-disciplinary strategy for enzyme discovery used to identify and characterize a family of cholesterol dehydrogenases from gut bacteria that facilitate the metabolism of cholesterol to coprostanol in the gastrointestinal tract. [Kenny et al Cell Host & Microbe 2020 Aug 12;28(2):245-257 PMID:32544460]

QUALIFICATIONS

  • Strong publication record and excellent communication skills.

  • Excellent organization and time management skills required.

  • Ability to use sound judgment to handle a variety of tasks and to shift priorities simultaneously as well as to effectively solve problems.

All Broad employees regardless of work location must be fully vaccinated for COVID-19 by Tuesday October 12 2021. Requests for exemption for medical or sincerely held religious beliefs will be considered.

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All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin disability or protected veteran status.

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Posting Date: Oct 16, 2021
Closing Date:
Organisation Website/Careers Page: https://broadinstitute.wd1.myworkdayjobs.com/en-US/broad_institute/job/Cambridge-MA/Postdoctoral-Associate---Xavier-Lab_4637


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