Job Description:
The Company
Dyno Therapeutics is reshaping the gene therapy landscape through AI-powered vectors. Through the application of our transformative technologies and strategic partnerships with leaders in gene therapy, we believe a future with life changing gene therapies for millions of people is within reach.
Our team includes world-class molecular and synthetic biologists, protein engineers and gene therapy scientists working alongside software engineers, data scientists, and machine learning experts to transform the landscape of available gene therapy capsids. Dyno was named Startup of the Year in 2020 by Xconomy, Endpoints 11 in 2021, and one of America’s Best Startups in 2022 and by Forbes!
The Role
Scientist I/II - Computational Biologist, Capsid Data Science. Computational Biology is at the heart of Dyno’s platform, and your work as a part of the Capsid Data Science team can have a major impact on the future of gene therapy. The Capsid Data Science team focuses on translating our data into scientific insights and iterative capsid design. The team has a central role in synthesizing data from across Dyno to identify and evaluate top capsids in the context of our product goals. Computational scientists and engineers on the team work together to generate data-driven insights and outputs that drive machine learning models and strategic decision-making.
How You Will Contribute
As a Scientist I/II - Computational Biologist, Capsid Data Science, you will lead analysis of biological data in a statistically rigorous manner and communicate findings to stakeholders across Dyno. This is a highly collaborative position working closely with other scientists and stakeholders to enable decision-making based on the data collected at Dyno.
Responsibilities:
- Analyze and explore large, complex datasets to evaluate capsid performance
- Develop statistical and analysis methods for interpreting data from high-throughput capsid studies
- Contribute to candidate selection and study design for validation of top AAV capsids
- Collaborate with machine learning teams in applying datasets to improve capsid design models
- Collaborate with software engineers to streamline data processing workflows
- Communicate technical results and methods to scientists and stakeholders from diverse teams
Who You Are
- Trusted partner
- Team oriented
- Thoughtful & detail oriented
- Work with a sense of urgency
- Appreciate opportunities at the intersections of data science and biology
- Thrives in a fast paced working environment
- Curious and unafraid to ask questions
Basic Qualifications
- Ph.D. in computational biology, statistics, physics (or related quantitative fields) or equivalent experience
- Strong foundation in data analysis and statistical methods
- Experience working with large scale biological datasets
- Experience developing code in Python for computational workflows
- Demonstrated independence in leading research projects or collaborations
Preferred Qualifications
- Experience with NGS data analysis
- Internship or work experience in an industry setting
- Publications in peer-reviewed journals or conferences
- Familiarity with software engineering best practices
- Familiarity with molecular biology, protein engineering, gene therapy, and/or AAV biology
|
