Associate Principal Scientist, Clinical Computational Biology

At Bayer were visionaries driven to solve the worlds toughest challenges and striving for a world where Health for all Hunger for none is no longer a dream but a real possibility. Were doing it with energy curiosity and sheer dedication always learning from unique perspectives of those around us expanding our thinking growing our capabilities and redefining impossible. There are so many reasons to join us. If youre hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference theres only one choice.

Associate Principal Scientist Clinical Computational Biology

In Bayer Research & Early Development Oncology we discover the next generation of cancer therapies with scientific innovation hubs in Berlin Boston Basel and Oslo.  Translational Sciences Oncology is a multidisciplinary department that harnesses cutting-edge technologies to enable earlier detection precise molecular diagnosis and personalized treatment for cancer patients.  We ensure seamless translational support starting from the assessment of new targets through to preclinical and clinical studies from first-in-human through lifecycle management.

This role of an Associate Principal Scientist Clinical Computational Biology is responsible for evaluating DNA-seq RNA-seq and/or imaging data for oncology clinical development programs.  As a computational biology expert you will provide data packages and recommendations to translational science teams for Early or Late Development clinical programs.  The scientist will make significant contributions to cross-functional initiatives and collaborations on exploratory data analysis for clinical biomarkers.  The introduction adaptation and further development of highly innovative bioinformatics methods to analyze multi-omics data sets is a key activity.  In addition he or she will contribute to reverse translation efforts for disease understanding across multiple clinical programs in the same indication.

YOUR TASKS AND RESPONSIBILITIES

The primary responsibilities of this role Associate Principal Scientist Clinical Computational Biology are to:

• Identification of novel biomarkers using state-of-the-art bioinformatics methods in the exploratory analyses of -omics and/or imaging data from oncology clinical trial specimens;
• Collaborate across cross-functional teams to evaluate translational science questions from clinical programs;
• Contribute to Biomarker Evaluation Plans Biomarker Evaluation Reports data packages for stage gate decisions and external publications;
• Development evaluation implementation and application of bioinformatics and statistical methods on DNA-seq RNA-seq or imaging datasets;
• Involved in collaborations with academic or commercial partners. Represents occasionally Bayer in external networks in the field of Bioinformatics;
• Maintains interfaces among Translational Science teams Biomarker Statistics and IT functions.

WHO YOU ARE

Your success will be driven by your demonstration of our LIFE values. More specifically related to this position Bayer seeks an incumbent who possesses the following:

Required Qualifications:

• PhD in Sciences (Bioinformatics Chemistry Biology Genetics Biomedical Engineering Physics Computer Science Informatics or other related quantitative discipline) with demonstrated peer-reviewed publications in computational biology;
• 2+ years’ experience in pharmaceutical or biotech company;
• Demonstrated experience in statistical analysis of DNA-seq RNA-seq single-cell or imaging datasets in oncology with proficiency in a programming environment (such as R or Python);
• Independently prioritizes tasks and delivers high-quality technical recommendations;
• Strong critical thinking and learning agility;
• Proficient at communicating and collaborating in cross-functional teams.

Preferred Qualifications:

• Previous experience analyzing clinical trial biomarker data.