- Job ID:
- 32963
- Location:
- 450 Brookline Ave
Boston
MA 02215
- Category:
- Fellowships
- Employment Type:
- Full time
- Work Location:
- PTL Remote: 2-3 days remote/wk
Overview
A full-time computational biology postdoctoral research fellow position is available in the laboratory of Dr. Brian Crompton in the Department of Pediatric Oncology at the Dana-Farber Cancer Institute for a highly motivated individual. The Crompton laboratory is recruiting a postdoctoral research fellow to focus on analysis of multi-dimensional genomic data generated from highly unique cohorts of patient samples. The fellow will also work on developing novel computational algorithms and adapting existing tools to unique scenarios.
The Crompton laboratory specializes in using a combination of next-generation sequencing approaches to profile tumor biopsies germline samples and liquid biopsies (including circulating tumor DNA and circulating tumor cells) collected from patients with aggressive childhood solid tumors. Serial tissue from the largest phase 3 trials in North America are studied in our laboratory using a wide range of techniques. Approaches include custom hybrid capture sequencing whole-genome sequencing digital droplet PCR single-cell RNA-sequencing single-cell proteomics methylation profiling ATAC-Seq and ChIP-Seq. The postdoctoral research fellow will lead computational projects studying these data to identify prognostic biomarkers of outcome recurrent patterns of tumor evolution and identify mechanisms of treatment resistance in the most aggressive solid malignancies effecting children.
Located in Boston and the surrounding communities Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer HIV/AIDS and related diseases. We strive to create an inclusive diverse and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment we educate tomorrow's physician/researchers and we work with amazing partners including other Harvard Medical School-affiliated hospitals.
Responsibilities
The postdoctoral research fellow will work in a rich educational environment. The laboratory is situated in an ideal academic setting with unparalleled access to collaborators throughout the Harvard Medical School system and affiliated hospitals. Our proximity to a major hub of medical industry also creates opportunities for collaborations with industry leaders in cancer therapeutics and clinical cancer genomics. The fellow will work closely with clinical trialists wet bench scientists post-docs and technicians as well as other computational experts in our group. In this role the postdoctoral research fellow will also receive teaching and mentorship from world-renowned computational biologists in the area including those at Dana-Farber and the Broad Institute where Dr. Crompton has academic appointments and many ongoing collaborations. Mentorship of the candidate will focus on the development and publication of high-impact research projects and preparing the fellow for a career as an independent academic investigator or for a position in the biomedical industry.
Qualifications
- PhD MD MD/PhD or doctoral equivalent
- Mastery of laboratory bench techniques
- Experience with computational analyses
- Willingness to learn and master new laboratory and computation techniques
- Excellent written and oral communication skills
- Strong organizational skills including the ability to handle a variety of tasks in a fast-paced environment
- Two-year availability preferred
At Dana-Farber Cancer Institute we work every day to create an innovative caring and inclusive environment where every patient family and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals neither do we. If working in this kind of organization inspires you we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race color religion sex gender identity or expression national origin sexual orientation genetic information disability age ancestry military service protected veteran status or other groups as protected by law.
