The life sciences are in the midst of a data revolution. Cheap and accurate genome sequencing is a reality, high-resolution imaging is becoming routine, and clinical data is increasingly stored in machine-readable formats. These breakthroughs have brought us to the threshold of a new era in biomedicine, one where the data sciences hold the potential to propel our understanding and treatment of human disease. The Broad Institute’s Data Sciences Platform sits at the center of this transformation. Our team is charged with building a suite of sophisticated genomic analysis tools to serve both the Institute and the world. We play a pivotal role in flagship scientific efforts that will be part of the history of science, such as the All of Us Cohort Program, the Human Cell Atlas, and the NIH Data Commons; we collaborate with world leading technology corporations, philanthropic organizations, and pharmaceutical companies to transform the way biomedical research is done; we have assembled an exceptional team of data scientists who create software products that are used to analyze data all around the world. Together, these activities make us one of the preeminent organizations at the intersection of the life sciences and data sciences. We seek a brilliant and energetic individual that can further our mission. This individual will help analyze different types of sequencing data and develop tools and methods to improve them. The ideal candidate will provide computational expertise to the Institute’s sequencing center, and as such will be on the cutting edge of DNA sequencing technology, often working with data from brand new or pre-release technologies, as well as advising and participating in the development of new lab protocols and computational methods. They will be responsible for reporting their findings to a broad range of colleagues with varying degrees of expertise. A background in biology is not required for this position, although experience with genomics and DNA sequencing data is preferred. Job Responsibilities Devise new algorithms and approaches to data analysis. Rapidly prototype these ideas, validating them on novel data sets. Be involved in the effort to implement and optimize successful algorithms in the pipeline and for use by the broader community. Investigate interesting and sometimes puzzling data. Gather information from, and present results to a broad range of non-computational staff. Prepare written reports and presentations for internal use and publication. Requirements PhD degree or equivalent work experience in Computer Science, Mathematics, Bioinformatics, Physics or a related field Excellent oral and written English communication skills Ability to solve complex problems individually and as part of a team Any of the following preferred (but not required) Experience developing software in one or more modern programming languages, with Java or C++ preferred Experience with genomics and sequencing technologies Familiarity with version control systems such as git or subversion What we offer: A fun, collaborative and mission-driven environment The chance to have a real impact on the advancement of science and medicine Comprehensive benefits package: Lots of paid time off (including vacation time, holidays, parental leave, and sick time), health/dental care, matching 401K, commuter benefits, child care, tuition reimbursement and more (see https://www.broadinstitute.org/benefits/benefits-working-broad) A background in biology is not required for this position, although experience with genomics and DNA sequencing data is preferred. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.