The Position The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Senior Scientist to study the molecular pathways that contribute to neurological diseases including Alzheimer’s Disease and Multiple Sclerosis. The applicant will work with colleagues in Translational Genomics and Neuroscience departments to pursue novel therapeutics and biomarkers for disease areas of focus in the Neuroscience department. The applicant will lead a data-driven research program generating and leveraging high-dimensional ‘omic data from both in vitro human cell models and patient-derived tissue and biofluids. Qualifications Desired background: PhD plus Postdoctoral training in Computational Biology, Molecular Biology, Neuroscience or related field; or equivalent Previous leadership experience in an independent position such as industrial scientist or professor, in a computational biology role that resulted in impactful scientific insights and publications Ability to define and lead a research agenda involving the creative analysis and integration of high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data and CRISPR screen analysis), and, in close collaboration with bench scientists, the experimental development of resulting ideas. Experience studying the biology of neurological disease and eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology. Ability to work successfully as the bioinformatics lead in cross-functional teams that contribute to drug and biomarker development. Excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars
