The position of Postdoctoral Fellow (PDF) -- with an emphasis on computational cancer genomics -- is immediately available at The Cancer Science Institute of Singapore (a part of The National University of Singapore). The postholder will work with the laboratories of Prof. Ashok Venkitaraman, on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.
This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.
The postholder will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (eg., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Prof. Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.
