Computational Genomics Senior Research Scientist (Method Development)
Organisation Name: Vertex
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Country: United States
Job Description:
Job Description
We are seeking a computational biologist with expertise in algorithm and method development to join Vertex. This position is part of a rapidly growing Data and Computational Sciences team focused on Cell and Genetic therapies for diseases with serious unmet need. You will play a critical key role in developing cutting-edge computational methods that assess the safety and efficacy of transformative gene editing therapeutics for our program. You will also cross-functionally collaborate with project teams to design and analyze large-scale genomic datasets to prototype new technologies. A strong background in computational methods development and an ability to seamlessly collaborate with team members will be required for success in this role.
Key responsibilities:
Develop novel computational methods that address key questions regarding the efficacy and safety of gene editing therapeutics
Leverage and extend best practices from the genomics, data science and software-engineering to create industry-leading analysis software
Collaborate with project teams to identify key needs and questions that can be addressed using genomics
Lead rigorous computational analyses of sequencing data and other biological data from gene editing experiments
Education and Experience:
Ph.D. (or equivalent degree) in computational biology, bioinformatics, computer science, human genetics, or genomics or an MS (or equivalent degree) in similar fields with 2-5+ years of productive employment
MS (or equivalent degree) in similar fields and 5+ years of productive, relevant employment experience, or
BS (or equivalent degree) in similar fields and 8+ years of productive, relevant employment experience
A proven track record of next-generation sequencing (NGS) methods development pertaining to variant calling, RNA-Seq, amplicon sequencing or related data types
A strong programming background, with expertise in python, Rust and/or C++
An independent, detail-oriented, and self-motivated approach to problem solving
A team-oriented mindset that welcomes feedback and supports others
Strong organizational and time-management skills
Excellent presentation and communication skills, including the ability to tailor scientific content to audiences with different backgrounds
Familiarity with high-performance computing, cloud computing and bioinformatics workflow languages are a plus
Salary range: $126,00 - $190,200annually
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
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Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note that Vertex requires COVID-19 vaccination for all employees working in the U.S. as a condition of employment at Vertex, subject to medical, religious or other accommodations or exemptions required by law. We believe this requirement is vital to keeping everyone at Vertex and in our communities safe. This requirement applies to both existing and new employees who may at any time work on-site at a Vertex facility or visit another location on behalf of Vertex (e.g., conferences, customer visits, etc.), including all remote employees. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
