We are powering the age of immune medicine–you can too. At Adaptive, our goal is to harness the power of the adaptive immune system to make a difference in the lives of people living with many different diseases.
As an Adapter, you will be surrounded by driven colleagues who think boldly and innovate fearlessly. You will experience meaningful challenges in your work and be fueled by the knowledge that you’re making a difference in patient’s lives.
You belong here – come discover your story at Adaptive.
Position Overview
The Antigen Map project is a collaboration between Adaptive and Microsoft Healthcare to map and decode the human immune system, nature’s most finely tuned diagnostic. Together, we are using immunosequencing, proprietary computational modeling and machine learning to map T-cell receptor (TCR) sequences to the antigens they bind. Using this data, we aim to translate the natural diagnostic capability of the immune system into the clinic.
The Antigen Map is seeking a thoughtful computational biologist/data scientist who is enthusiastic about fields like biostatistics, data analysis, machine learning, the immune system, clinical data, and improving human health. You will join a team within the Antigen Map that is mining large clinical datasets and proprietary immunological assays for disease-associated TCRs and using them to understand diseases and build machine learning-based diagnostics for cancer, autoimmune, and infectious diseases.
We are looking for a computational scientist interested in working with and/or leading disease-focused research, particularly in autoimmune diseases, with strong experience in machine learning and data science on large datasets.
Strong candidates will have substantial experience in solving challenging problems in biological datasets and communicating results to diverse audiences. They will also have demonstrated the ability to work independently and as part of an interdisciplinary team. Adaptive strongly values professional development, and we are committed to helping team members grow in their careers.
Key Responsibilities and Essential Functions
- Perform quick and thorough analyses of DNA sequencing of T-cell receptors and other clinical data to understand confounders, make descriptive figures, and address key scientific questions.
- Develop and apply robust machine learning methods that combine biological insights with rapidly evolving data.
- Communicate with internal and external collaborators to design experiments and manage clinical metadata
- Present results to a wide variety of stakeholders, from wet lab and computational scientists to clinical, commercial, and executive team members
- BE A PROBLEM SOLVER: communicate well, ask questions, proactively eliminate bottlenecks, and be the person people go to when they want a job done right
Position Requirements (Education, Experience, Other)
Required
- Graduate degree PhD in Computer Science, Statistics, Biostatistics, Genomics, or related field and 4+ years of relevant experience (or a Master’s degree with 12+ years of experience)
- Proficiency in Python
Preferred
- Demonstrated ability to work on multidisciplinary teams
- Experience in presenting technical material to diverse audiences
- Experience with detailed analysis of next-generation sequencing datasets
- (Preferred) Experience with clinical data and samples (e.g., clinical trials, observational studies)
- (Preferred) Extensive experience and domain knowledge in infectious or autoimmune disease
Working Conditions
Work is performed in an office environment
#LI-Remote
Interested in this position, but don’t meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn’t match all the qualifications; you may be the exact candidate we’re searching for!
Adaptive Biotechnologies is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Equal Opportunity Employer/Veterans/Disabled
Interview accommodations may be requested during initial interview scheduling communications.
NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.