The life sciences are in the midst of a data revolution. Cheap and accurate genome sequencing is a reality, high-resolution imaging is becoming routine, and clinical data is increasingly stored in machine-readable formats. These breakthroughs have brought us to the threshold of a new era in biomedicine, one where the data sciences hold the potential to propel our understanding and treatment of human disease. The Broad Institute’s Data Sciences Platform sits at the center of this transformation. Our team is charged with building a suite of sophisticated genomic analysis tools to serve both the Institute and the world. We play a pivotal role in flagship scientific efforts that will be part of the history of science, such as the All of Us Cohort Program, the Human Cell Atlas, and the NIH Data Commons; we collaborate with world leading technology corporations, philanthropic organizations, and pharmaceutical companies to transform the way biomedical research is done; we have assembled an exceptional team of data scientists who create software products that are used to analyze data all around the world. Together, these activities make us one of the preeminent organizations at the intersection of the life sciences and data sciences. We seek a curious and energetic individual that can further our mission. This individual will help create, validate, and maintain tools and pipelines to process and analyze different types of sequencing data. The team they will be joining provides computational expertise to the Institutes’ sequencing center; as such, the individual will be on the cutting edge of DNA sequencing technology, often working with data from brand new technologies, as well as advising and participating in the development of new lab protocols and computational methods. They will also be part of the first line of defense tasked with data exploration and problem solving when unusual or confusing data is produced by the center. They will be responsible for reporting their findings to a broad range of colleagues with varying regions of expertise. A background in biology is not required for this position. Job Responsibilities · Devise new algorithms and approaches to data analysis. · Rapidly prototype these ideas, validating their value on novel data sets. · Be involved in the effort to implement and optimize successful algorithms in the pipeline and for use by the broader community. · Investigate interesting and sometimes puzzling data. · Gather information from, and present results to a broad range of non-computational staff. · Prepare written reports and presentations for internal use and publication. Requirements · Ph.D. in Computer Science, Mathematics, Bioinformatics, Physics or a related field · Excellent oral and written English communication skills · Ability to solve complex problems individually and as part of a team · Experience developing software in one or more modern programming languages Any of the following is a plus (but NOT required) · Familiarity with Java preferred but not required · Familiarity with R or Python preferred but not required · Familiarity with version control systems such as git or subversion preferred but not required What we offer: · A fun, collaborative and mission-driven environment · The chance to have a real impact on the advancement of science and medicine · Comprehensive benefits package: Lots of paid time off (including vacation time, holidays, parental leave, and sick time), health/dental care, matching 401K, commuter benefits, child care, tuition reimbursement and more (see https://www.broadinstitute.org/benefits/benefits-working-broad) EOE / Minorities / Females / Protected Veterans / Disabilities #LI-POST All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.