Organisation Name: Oregon Health & Science University
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Department Overview The Oregon National Primate Research Center (ONPRC) is located 12 miles west of the OHSU main campus, and sits on 162 acres of land featuring forested areas, research and administration buildings, indoor and outdoor animal housing, a pond, and 2-mile perimeter walking path. Our mission is to improve human health and the quality of life through the support of nonhuman primate research programs that advance our knowledge of the causes, preventions, treatments, and cures of debilitating diseases. Function/Duties of Position The Oregon National Primate Research Center is searching for an enthusiastic computational scientist to join a team developing novel applications of single cell RNA sequencing (scRNA-seq) to better understand infectious disease pathogenesis and aid vaccine development. The applicant will lead the analysis of single-cell RNA-seq data from T cells and other lymphocyte subsets using established and novel methods. The work may also include TCR clonotype analyses, and non-single cell data such as bulk RNA-seq or epigenetic assays. The applicant will ideally be able to perform self-directed exploration and analysis of complex datasets, in addition to analyses under the direction of supervisors. This position requires a hardworking, dedicated individual who has careful attention to detail. Strong computational skills are required for data analysis and documentation, along with the ability and willingness to translate from computation into the underlying biology. Experience with scRNA-seq is not required, though is an advantage. Must interact and communicate effectively with bioinformatics and wet lab team members. This position does not require direct work with non-human primates. Required Qualifications Master's degree in Biology, Computer Science or related field and 3 years of relevant experience; OR Bachelor’s degree with major courses in field of research and 5 years of relevant experience At least one-year relevant research experience in bioinformatic analysis of next-generation sequencing data Successful research in a computational field demonstrated by co-authorship on at least one publication Ability to communicate effectively, in both written and oral formats Ability to work both independently and in a small group setting, and one-on-one with collaborators in a positive and productive manner Working knowledge of at least one programming language Demonstrated independence and competence to perform data management and analysis of research finding, including use of relevant R packages, spreadsheets, graphics and statistical programs Ability to prioritize work demands, and coordinate research protocols with other staff Organizational skills and careful attention to details to satisfactorily perform job duties Quality control and review of data skills High level of self-motivation and integrity Requires extensive work with a computer and could include sitting at a desk for long periods Able to perform the essential functions of the position with or without accommodation Preferred Qualifications Master's degree in Bioinformatics Experience in Illumina-based short read sequence analysis, programming in “R, python, and Linux based informatics software Previous experience with RNAseq analysis is preferred Ability to problem solve, produce clear documentation of work, produce graphical summaries of data, contribute to the writing of manuscripts, and grant applications Demonstrated experience in problem solving Additional Details Apply here online. Please be sure to upload a cover letter, CV/resume and references. All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.
