The Position The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Scientist to study the molecular pathways that contribute to neurological diseases including Alzheimer’s Disease and Multiple Sclerosis. Applicant will work with colleagues in Translational Genomics and Neuroscience departments to pursue novel therapeutics and biomarkers for disease areas of focus in the Neuroscience department. The applicant will lead a data-driven research program generating and leveraging high-dimensional ‘omic data from both in vitro human cell models and patient-derived tissue and biofluids. Qualifications Postdoctoral training, or exceptional PhD experience, in Bioinformatics, Biostatistics, Computational Biology or similar field, including familiarity and a strong desire to work in the field of Neuroscience. Strong scientific publication record Ability to creatively analyze and integrate high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data, CRISPR screen analysis, etc.) to generate new biological insights, and then work closely with bench scientists to develop those ideas experimentally. Demonstrated competence in languages such as R or Python for bioinformatics analyses. Experience thinking about the biology of neurological disease and eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology. Ability to work successfully as the bioinformatics lead in cross-functional teams that contribute to drug and biomarker development. Excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars
